Publications

2018


Characterisation of neonatal seizures and their treatment using continuous EEG monitoring: a multicentre experience.

2017

A Temko, AK Sarkar, GB Boylan, S Mathieson, WP Marnane, G Lightbody.

Toward a Personalized Real-Time Diagnosis in Neonatal Seizure Detection 2017. IEEE Journal of Translational Engineering in Health and Medicine 5, 1-14

2016

Kirkpatrick, M. and Jollands, A. (2016),

Sharks, ice cream, and neonatal seizures.

Dev Med Child Neurol. doi:10.1111/dmcn.13288

Kharoshankaya, L., Stevenson, N. J., Livingstone, V., Murray, D. M., Murphy, B. P., Ahearne, C. E. and Boylan, G. B. (2016),

Seizure burden and neurodevelopmental outcome in neonates with hypoxic–ischemic encephalopathy.

Dev Med Child Neurol. doi:10.1111/dmcn.13215

Ahmed, R., Temko, A., Marnane, W., Lightbody, G., & Boylan, G.

Grading hypoxic–ischemic encephalopathy severity in neonatal EEG using GMM supervectors and the support vector machine.

Clinical Neurophysiology2016, 127(1), 297-309.

Donovan, M. D., Griffin, B. T., Kharoshankaya, L., Cryan, J. F., & Boylan, G. B.

Pharmacotherapy for neonatal seizures: Current knowledge and future perspectives. 

Drugs2016, 76(6), 647-661.

Low, E., Stevenson, N. J., Mathieson, S. R., Livingstone, V., Ryan, A. C., Rennie, J. M., & Boylan, G. B.

Short-Term Effects of Phenobarbitone on Electrographic Seizures in Neonates. 

Neonatology 2016, 110(1), 40-46.

Donovan, M. D., Boylan, G. B., Murray, D. M., Cryan, J. F., & Griffin, B. T.

Treating disorders of the neonatal central nervous system: pharmacokinetic and pharmacodynamic considerations with a focus on antiepileptics.

British journal of clinical pharmacology 2016, 81(1), 62-77.

Mathieson, S. R., Stevenson, N. J., Low, E., Marnane, W. P., Rennie, J. M., Temko, A., … & Boylan, G. B.

Validation of an automated seizure detection algorithm for term neonates. 

Clinical Neurophysiology 2016, 127(1), 156-168.

Kharoshankaya, L., Murray, DM., Bogue, C., Ahearne C.

Early EEG findings in Tuberous Sclerosis Complex presenting with apneic seizures soon after birth

Clinical Neurophysiology, 2016 [In Press]

Mathieson S, Rennie J, Livingstone V, Temko A, Low E, Pressler RM, Boylan GB.

In-depth performance analysis of an EEG based neonatal seizure detection algorithm.

Clin Neurophysiol. 2016 May;127(5):2246-56. doi: 10.1016/j.clinph.2016.01.026. Epub 2016 Feb 21.

Jullien V, Pressler RM, Boylan G, Blennow M, Marlow N, Chiron C, Pons G; NEMO Consortium Neonatal Seizure Treatment With Medication Off-Patent.

Pilot evaluation of the population pharmacokinetics of bumetanide in term newborn infants with seizures.

J Clin Pharmacol. 2016 Mar;56(3):284-90. doi: 10.1002/jcph.596. Epub 2015 Sep 14.

Weeke LC, Boylan GB, Pressler RM, Hallberg B, Blennow M, Toet MC, Groenendaal F, de Vries LS; NEonatal seizure treatment with Medication Off -patent (NEMO)consortium.

Role of EEG background activity, seizure burden and MRI in predicting neurodevelopmental outcome in full-term infants with hypoxic-ischaemic encephalopathy in the era of therapeutic hypothermia.

Eur J Paediatr Neurol. 2016 Jun 20. pii: S1090-3798(16)30086-1. doi: 10.1016/j.ejpn.2016.06.003. [Epub ahead of print]

Weeke LC, Toet MC, van Rooij LG, Groenendaal F, Boylan GB, Pressler RM, Hellström-Westas L, van den Broek MP, de Vries LS.

Lidocaine response rate in aEEG-confirmed neonatal seizures: Retrospective study of 413 full-term and preterm infants.

Epilepsia. 2016 Feb;57(2):233-42. doi: 10.1111/epi.13286. Epub 2015 Dec 31.

Janáčková S, Boyd S, Yozawitz E, Tsuchida T, Lamblin MD, Gueden S, Pressler R.

Electroencephalographic characteristics of epileptic seizures in preterm neonates.

Clin Neurophysiol. 2016 Aug;127(8):2721-7. doi: 10.1016/j.clinph.2016.05.006. Epub 2016 May 24.

PMID: 27417043

Mathieson, Sean R., Livingstone, Vicki, Low Evonne, Pressler Ronit, Rennie Janet M., Boylan Geraldine B.

Phenobarbital reduces EEG amplitude and propagation of neonatal seizures but does not alter performance of automated seizure detection.

Clinical Neurophysiology 2016 [In Press].

Dunne Jonathan M, Wertheim David, Clarke Paul, Kapellou Olga, Chisholm Philippa, Boardman James P, Shah Divyen K.

Automated electroencephalographic discontinuity in cooled newborns predicts cerebral MRI and neurodevelopmental outcome

Arch Dis Child Fetal Neonatal Ed  2016 [In Press] doi:10.1136/archdischild-2015-309697

2015

Temko A, Marnane W, Boylan G, Lightbody G.

Clinical implementation of a neonatal seizure detection algorithm

Decision Support Systems 2015;70:86-96. doi:10.1016/j.dss.2014.12.006.

Nathan J. Stevenson, Robert R. Clancy, Sampsa Vanhatalo, Ingmar Rosén, Janet M. Rennie, Geraldine B. Boylan.

Interobserver agreement for neonatal seizure detection using multichannel EEG

Annals of Clinical and Translational Neurology. October, 2015 10.1002/acn3.249

Geraldine B. Boylan, Liudmila Kharoshankaya, Courtney J. Wusthof.

Seizures and hypothermia: Importance of electroencephalographic monitoring and considerations for treatment

Cooling After Perinatal Asphyxia. Seminars in Fetal and Neonatal Medicine Volume 20, Issue 2, April 2015, Pages 103–108

Goulding, R. M., Stevenson, N. J., Murray, D. M., Livingstone, V., Filan, P. M., & Boylan, G. B.

Heart rate variability in hypoxic ischemic encephalopathy: correlation with EEG grade and 2-y neurodevelopmental outcome

Pediatric research 2015 May;77(5):681-7. doi: 10.1038/pr.2015.28. Epub 2015 Feb 9.

2014

Temko A, Marnane W, Boylan G, O’Toole JM, Lightbody G.

Neonatal EEG audification for seizure detection

Conf Proc IEEE Eng Med Biol Soc. 2014;2014:4451-4. doi: 10.1109/EMBC.2014.6944612.

Stevenson NJ, Palmu K, Wikström S, Hellström-Westas L, Vanhatalo S.

Measuring brain activity cycling (BAC) in long term EEG monitoring of preterm babies

Physiol Meas. 2014 Jul;35(7):1493-508. doi: 10.1088/0967-3334/35/7/1493. Epub 2014 Jun 5.

Kharoshankaya L, Filan PM, Bogue CO, Murray DM, Boylan GB.

Global suppression of electrocortical activity in unilateral perinatal thalamic stroke

Dev Med Child Neurol. 2014 Jul;56(7):695-8. doi: 10.1111/dmcn.12365. Epub 2014 Jan 11.

2013

Temko A, Boylan G, Marnane W, Lightbody G.

Robust neonatal EEG seizure detection through adaptive background modeling

Int J Neural Syst. 2013 Aug;23(4):1350018. doi: 10.1142/S0129065713500184. Epub 2013 Jun 4.

Boylan GB, Stevenson NJ, Vanhatalo S.

Monitoring neonatal seizures

Semin Fetal Neonatal Med. 2013 Aug;18(4):202-8. doi: 10.1016/j.siny.2013.04.004. Epub 2013 May 24. Review.

2012

Temko A, Stevenson N, Marnane W, Boylan G, Lightbody G.

Inclusion of temporal priors for automated neonatal EEG classification.

J Neural Eng. 2012 Aug;9(4):046002. doi: 10.1088/1741-2560/9/4/046002. Epub 2012 Jun 19.